Table 4. Known and potentially novel genes identified as components of steroidogenesis in humans.
These 45 genes were determined from the overlap between genes differentially expressed in the adrenal gland vs. control (log 2FC≥2) and in the testis vs. control (log 2FC≥1).
| Steroidogenesis |
| CYP17A1, CYP11A1, STAR, FDX1P1, FDX1, PAPSS2, HSD3B2, POR |
| Cholesterol metabolism & oxidative stress |
|
SERPINA5, SCARB1, DHCR24, APOA1, APOC1, MSMO1, AS3MT, LDLR, DHCR7,
ACSS1, NPC1, PDK4, ABCA5, IDI1, GPD1L, HMGCR |
| Oxidative stress |
| GSTA1, MGST1, SLC8B1, GSTA3 |
| Novel |
|
MGARP (OSAP), MAP3K15, HPGD, C7, MT2A, DLK1 (PREF1), INHA, FOXO4,
GRAMD1B, RMDN2, SLC46A3, SLC16A9, COL15A1, AVPI1, FRRS1, VCAM1, FLJ38894 |