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. Author manuscript; available in PMC: 2017 Apr 27.
Published in final edited form as: Arthritis Rheumatol. 2014 Jan;66(1):68–77. doi: 10.1002/art.38198

Figure 4. Increased induction of IL -10 by Fas deficient macrophages in response to IL-1β and gp96.

Figure 4

In vitro bone marrow-derived macrophages from controland Fasf/f, LyzMcre mice were activated by recombinant IL-1β (5 ng/ml) or gp96 (5 μg/ml) for 4 or 20 hours. The concentrations of IL-6 (A), CXCL5 (B) and IL-10 (C) in culture supernatants were determined by ELISA. Values were normalized for viable cell number by MTT. Data are mean ± SE of macrophages from 4 mice per group. * represents p < 0.05, and ** p < 0.01 between the indicated groups.