Table 3.

Group × Timepoint Interactions Predicting Average Blood Oxygen Level-Dependent (BOLD) Activity

Region	x	y	z	Voxels	BA	F	ηp2	Group Differences - Peak
Right Postcentral Gyrus	26	−33	52	162	3	4.45	0.10	DMDD>ADHD=HV
Right Declive	37	−75	−22	85	–	4.10	0.09	DMDD=HV>ADHD
Left Postcentral Gyrus	−30	−33	52	73	3	3.85	0.09	DMDD>ADHD=HV
Right Medial Frontal Gyrus	9	−19	52	72	6	3.69	0.09	DMDD>ADHD=HV
Left Thalamus	−2	−22	3	48	–	2.46	0.06	DMDD>ADHD=HV
Right Parahippocampal Gyrus	30	−36	−8	39	36	3.61	0.08	HV>DMDD>ADHD
Left Posterior Cingulate	−5	−54	24	39	31	2.77	0.07	DMDD=HV=ADHD
Right Cerebellar Tonsil	23	−47	−46	29	–	3.61	0.08	DMDD>HV>ADHD
Right Superior Frontal Gyrus	2	13	49	25	6	3.00	0.07	DMDD=HV>ADHD

Note: Regions showing significant group × timepoint effects on average BOLD activity in a whole brain analysis are presented here. Coordinates (x, y, z) are presented for the peak voxel in each region as well as the number of voxels exceeding the whole brain threshold. The Brodmann area (BA) for each region is also presented. The F-statistic and partial eta squared (n_p²) of the group × timepoint interaction were calculated on BOLD activity averaged across the region. All group × time interactions and main effects of time were significant (p<.05). Pair-wise group differences at the peak timepoint (3.75 seconds after stimulus onset) are summarized here; significant effects at p<.05 are noted in the Group Differences column. ADHD = attention-deficit/hyperactivity disorder; DMDD = disruptive mood dysregulation disorder; HV = healthy volunteer.