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NAH protected intestinal HS from shedding during CLP-induced sepsis. The mice received CLP operation with or without pretreatment with NAH. The levels of HS in the intestinal tissues at 4 and 24 hr after CLP were detected by immunohistochemistry. This figure shows the representative image from each group (n=5; scale = 50 µm). Abbreviations: NAH, N-desulfated/re-N-acetylated heparin; HS, heparan sulfate; CLP, cecal ligation and puncture.
