Table 2.

Postischemic metabolic parameters

	Tw = 0 min	Tw = 30 min	Tw = 60 min	Tw = 90 min	Tw = 120 min
MVO2 (mL/min/g) Control	1.3 ± 0.2	1.5 ± 0.2*	1.6 ± 0.3*	1.7 ± 0.3*	1.5 ± 0.3
Deltorphin D	1.2 ± 0.2	1.7 ± 0.1*	1.8 ± 0.1*	1.6 ± 0.1*	1.4 ± 0.2
Cariporide	1.4 ± 0.1	2.0 ± 0.2*	2.1 ± 0.4*	2.1 ± 0.2*	1.8 ± 0.2
Lactate µg/min/g) Control	59 ± 8	59 ± 10	44 ± 11	44 ± 17	25 ± 13*
Deltorphin D	57 ± 14	39 ± 9 †	24 ± 10*	15 ± 10*	27 ± 18*
Cariporide	80 ± 10	89 ± 21	56 ± 19	31 ± 7*	20 ± 7*

All values are mean ± SE.

Cariporide: 3 µM included in the reperfusion buffer; Control: no reperfusion therapy; Deltorphin D: 1 µM Deltorphin D included in the reperfusion buffer; T_w = 0 min, working mode initiation (∼30 min postreperfusion and Deltorphin D administration); Lactate: lactate efflux across the heart (in µg/min per gram heart weight); MVO₂: myocardial oxygen consumption (in mL O₂/ min per gram heart weight).

^*P < 0.05 versus T_w = 0 min (repeated measures ANOVA); †P < 0.05 versus cariporide (ANOVA).