Hemodynamic characteristics of porcine sepsis. *Significantly different from baseline (P < 0.05); #significantly different from control, nonseptic group (P < 0.05); data presented as means ± SD. (a) Heart rate (bpm) during progression of sepsis; closed squares, sepsis, open circles, control. (b) Cardiac output (normalized to the body weight) during progression of sepsis; closed squares, sepsis, open circles, control. (c) Systemic vascular resistance during progression of sepsis; closed squares, sepsis, open circles, control. (d) Mean arterial pressure during progression of sepsis; closed squares, sepsis, open circles, control. (f) Plasma levels of IL-6 and TNF-α during progression of sepsis; closed squares, TNF-alpha, open circles, IL-6