Table 3. NMR based assessment of K2T23 keto-enolic equilibrium.
Solvent | fDK |
---|---|
d12-cyclohexane | 0.508 |
d3-chloroform | 0.395 |
d2-Dichloromethane | 0.396 |
d3-Acetonitrile | 0.615 |
d6-Dimethylsulfoxide | 0.481 |
d4-Methanol | 0.470 |
Fraction of K2T23 in the diketo conformers in selected solvents as evaluated by NMR.