Table 1. Pharmacological stress with dipyridamole echocardiographic linear measurements to assess cardiac function before and after cell injection.
Data were represented by means ± SEM. P>0.05.
| After Stress | Placebo (n = 7) | 1x106 pASC/Kg (n = 6) | 2x106 pASC/Kg (n = 7) | 4x106 pASC/Kg (n = 5) | |||||
|---|---|---|---|---|---|---|---|---|---|
| Before injection | After injection | Before injection | After injection | Before injection | After injection | Before injection | After injection | ||
| Parameters | Mean±SEM | Mean ± SEM | Mean ± SEM | Mean ± SEM | Mean ± SEM | Mean ± SEM | Mean ± SEM | Mean ± SEM | |
| MI area | (%) | 10.08 ± 3.09 | 10.97 ± 4.02 | 10.27 ± 2.43 | 9.56 ± 2.62 | 10.22 ± 1.62 | 8.37 ± 1.34 | 12.51 ± 1.45 | 7.77 ± 1.16 |
| Septum | (mm) | 0.51 ± 0.11 | 0.58 ± 0.11 | 0.53 ± 0.10 | 0.61 ± 0.10 | 0.51 ± 0.08 | 0.54 ± 0.13 | 0.65 ± 0.17 | 0.51 ± 0.01 |
| PW | (mm) | 0.53 ± 0.18 | 0.41 ± 0.09 | 0.34 ± 0.05 | 0.43 ± 0.05 | 0.38 ± 0.02 | 0.38 ± 0.04 | 0.47 ± 0.15 | 0.46 ± 0.04 |
| EDD | (mm) | 4.14 ± 0.33 | 4.34 ± 0.32 | 4.16 ± 0.29 | 4.57 ± 0.51 | 4.44 ± 0.29 | 4.48 ± 0.65 | 4.16 ± 0.60 | 4.24 ± 0.57 |
| ESD | (mm) | 3.21 ± 0.60 | 3.60 ± 0.34 | 3.13 ± 0.44 | 3.66 ± 0.36 | 3.41 ± 0.32 | 3.57 ± 0.67 | 3.14 ± 0.60 | 3.17 ± 0.43 |
| LVSF | (%) | 22.92 ± 10.20 | 17.24 ± 4.79 | 24.88 ± 9.51 | 19.82 ± 6.31 | 23.28 ± 2.43 | 20.84 ± 5.79 | 24.64 ± 6.46 | 25.17 ± 2.34 |
| EDV | (cm3) | 76.83 ± 13.98 | 85.80 ± 15.65 | 77.40 ± 13.06 | 96.09 ± 29.69 | 90.19 ± 13.38 | 94.25 ± 30.86 | 79.26 ± 24.49 | 82.62 ± 25.07 |
| ESV | (cm3) | 43.66 ± 17.58 | 55.01 ± 12.00 | 39.92 ± 13.06 | 56.86 ± 15.26 | 48.59 ± 10.65 | 56.16 ± 23.13 | 41.59 ± 20.27 | 41.26 ± 12.70 |
| SV | (cm3) | 33.17 ± 9.34 | 30.79 ± 8.57 | 37.48 ± 13.87 | 39.23 ± 21.09 | 41.60 ± 2.84 | 38.10 ± 12.83 | 37.67 ± 11.40 | 41.36 ± 12.92 |
| LVEF | (%) | 44.96 ± 16.00 | 35.90 ± 8.63 | 48.36 ± 15.57 | 40.58 ± 10.61 | 46.73 ± 4.22 | 42.20 ± 10.34 | 48.73 ± 10.83 | 50.03 ± 3.76 |
| LV Penn Mass | (g) | 58.70 ± 20.60 | 59.23 ± 15.98 | 48.06 ± 13.94 | 68.80 ± 28.80 | 53.99 ± 11.08 | 59.05 ± 19.89 | 67.03 ± 24.94 | 55.88 ± 13.54 |
MI: myocardial infarction, PW: posterior wall, EDD: end-diastolic diameter, ESD: end-systolic diameter, LVSF: left ventricle shortening fraction, EDV: end-diastolic volume, ESV: end-systolic volume, SV: stroke volume, LVEF: left ventricle ejection fraction, LV: left ventricle.