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. 2017 Apr 27;12(4):e0176588. doi: 10.1371/journal.pone.0176588

Table 2. Odds ratios (OR) and 95% confidence intervals (CI) for association between opium and tobacco use during pregnancy and risk of preterm delivery.

Pregnancies
N
Events Crude
OR (95% CI)
Model A1
OR (95% CI)
Model B2
OR (95% CI)
N (%)
Opium
 Unexposed 905 55 (6.1) Reference
 Exposed 887 89 (10.0) 1.73 (1.22–2.45) 1.74 (1.21–2.45) 1.69 (1.16–2.44)
Tobacco and opium
 Unexposed 905 55 (6.1) Reference
 Exposed to opium only 677 61 (9.0) 1.53 (1.05–2.23) 1.56 (1.05–2.32) 1.51 (1.01–2.24)
 Exposed to tobacco and opium 210 28 (13.3) 2.38 (1.47–3.85) 2.40 (1.43–4.04) 2.37 (1.40–3.99)

1Adjusted for: maternal age, height, BMI, parity, husband’s occupation, infant sex, delivery method, and residential place.

2Adjusted for all covariates which are included in Model A plus hypertension during the pregnancy and small for gestational age.