Table 4.
Maternal-fetal outcomes in patients with r-AKI versus controls with baseline creatinine available
| Outcomes | r-AKI (n=105) | Cr-Controls (n=8971) | Crude OR (95% CI) | Adjusted OR (95% CI) | P Value |
|---|---|---|---|---|---|
| Maternal | |||||
| Gestation age at delivery, wk | 37.6±3.6 | 39.2±2.1 | n/a | n/a | <0.001 |
| Cesarean section | 40 (42) | 27 (2423) | 1.8 (1.2 to 2.7) | 1.7 (1.1 to 2.5) | 0.01 |
| Gestational hypertension | 27 (28) | 16 (1493) | 1.8 (1.2 to 2.9) | 1.6 (1.0 to 2.5) | 0.06 |
| Preeclampsia | 23 (24) | 4 (379) | 6.8 (4.2 to 10.8) | 6.5 (3.9 to 10.8) | <0.001 |
| Preterm preeclampsia, wk | |||||
| <37 | 10 (11) | 1 (106) | 9.9 (5.1 to 19.1) | 7.5 (3.6 to 15.6) | <0.001 |
| <34 | 7 (7) | 0.3 (31) | 29.8 (9.0 to 48.4) | 12.8 (4.6 to 35.2) | <0.001 |
| Fetal | |||||
| Perinatal death | 3 (3) | 0.8 (69) | 3.8 (1.2 to 12.4) | 3.3 (1.0 to 11.1) | 0.05 |
| Baby weight (live births), g | 3210±823 | 3379±570 | n/a | n/a | 0.05 |
| Small for gestational age | 15 (15) | 9 (776) | 1.9 (1.1 to 3.3) | 2.0 (1.1 to 3.6) | 0.02 |
| NICU admission | 26 (27) | 8 (740) | 3.9 (2.5 to 6.1) | 3.1 (1.9 to 5.1) | <0.001 |
| Composite fetal outcome | 40 (41) | 19 (1753) | 2.6 (1.8 to 4.0) | 2.5 (1.6 to 3.7) | <0.001 |
Data are presented as percentage (n) or mean±SD. Composite fetal outcome includes preterm delivery <37 weeks, NICU admission, fetal or neonatal death, and/or small for gestational age. Outcomes are adjusted for age, race, BMI, diastolic BP at first prenatal visit, history of diabetes, and parity. P values reflect the adjusted analysis for dichotomous outcome variables, and t tests were used for continuous outcome variables. Cr-Controls, controls with baseline creatinine available; n/a, not applicable.