Table 1.
Characteristics of older KT recipients by incident post-KT dementia and AD
| Characteristic | No Dementia n=38,606 | Dementia n=2312 | AD n=570 |
|---|---|---|---|
| Recipient factors | |||
| Age | 63.3 (5.8) | 65.8 (6.1) | 66.9 (5.8) |
| Women | 37.3 | 40.6 | 39.8 |
| Race | |||
| White | 52.8 | 53.9 | 53.2 |
| Black | 26.8 | 28.3 | 26.5 |
| Hispanic/Latino | 13.3 | 12.9 | 15.8 |
| Other/multiracial | 7.1 | 4.9 | 4.6 |
| Education | |||
| None | 0.8 | 1.1 | 1.1 |
| Grade school (0–8) | 8.2 | 8.8 | 9.8 |
| High school (9–12) or GED | 55.6 | 59.8 | 61.1 |
| College/technical school | 18.0 | 16.3 | 13.5 |
| Associate or bachelor degree | 11.4 | 8.4 | 9.7 |
| Postcollege graduate degree | 6.1 | 5.5 | 4.9 |
| Cause of ESRD | |||
| Glomerular diseases | 13.8 | 9.9 | 12.5 |
| Diabetes | 35.2 | 41.8 | 35.6 |
| Hypertension | 22.5 | 20.7 | 21.8 |
| Other causes | 28.5 | 27.6 | 30.2 |
| Body mass index | 27.9 (4.9) | 27.3 (4.7) | 26.8 (4.5) |
| Hypertension | 87.8 | 85.6 | 84.6 |
| Diabetes | 45.3 | 52.8 | 46.3 |
| Hepatitis C virus positive | 5.2 | 4.6 | 4.4 |
| Pre-emptive transplant | 4.1 | 4.1 | 4.0 |
| Years on dialysis | 3.1 (1.5–4.8) | 3.0 (1.4–4.6) | 3.1 (1.4–4.7) |
| Previous KT | 4.8 | 3.9 | 5.1 |
| Transplant factors | |||
| PRA | 16.7 (28.6) | 14.7 (26.3) | 14.9 (26.1) |
| ABO incompatible | 0.4 | 0.2 | 0 |
| 0 HLA mismatches | 9.2 | 10.9 | 9.3 |
| CIT>24 h | 30.2 | 33.7 | 35.3 |
| Donor factors | |||
| Age | 42.6 (15.6) | 42.4 (15.7) | 41.6 (15.8) |
| Women | 46.2 | 45.9 | 44.6 |
| Race/Ethnicity | |||
| White | 70.7 | 69.8 | 68.4 |
| Black | 13.0 | 14.5 | 14.0 |
| Hispanic/Latino | 12.8 | 12.4 | 13.7 |
| Other/multiracial | 3.5 | 3.3 | 3.9 |
| Donation after cardiac death | 6.3 | 4.3 | 3.3 |
| Expanded criteria donor | 22.5 | 23.2 | 21.9 |
| Hypertension | 25.8 | 25.6 | 24.6 |
| Diabetes | 6.2 | 5.9 | 4.4 |
| Hepatitis C virus positive | 2.0 | 2.2 | 2.3 |
Values are presented as percentages, median (interquartile range), or mean (SD). For time on dialysis median and interquartile range are presented. AD is a subtype of dementia; therefore, the AD cases are a subset of the dementia cases. Dementia and AD are ICD-reported diagnoses of dementia or AD. GED, General Educational Development test; PRA, panel reactive antibody; HLA, human leukocyte antigen; CIT, cold ischemia time.