Table 1.

TRB1 chip-seq studies

Reference	Gronved, L. et al 2015	Ramadoss, P. et al 2014	Ayers, S. et al 2014	Chatonnet, F. et al 2013
Model	mouse liver	mouse liver	cell culture	cell culture
Detection method	Monoclonal AB C1	biotin-streptavidin	biotin-streptavidin	biotin-streptavidin
Findings
DR4 is the most common TRE in positive targets	☑	☑	☑	☑
DR0 is associated with negative targets		☑
T3 induced recruitment of TR to TRE	☑	☑	☑
T3 independent interaction between TR and TRE	☑	☑	☑
Majority of T3 binding sites found in intragenic regions	☑	☑	☑	☑
Little TRB binding sites near negative target genes	☑	☑
RXRalpha heterodimer partner	Not done	☑	Not done	Not done
TR isoform specific binding sites	Not done	Not done	Not done	☑
Motif enrichment analysis for TF other than TR		☑	☑
T3 regulated DNAase hypersensitive sites	☑	☑	Not done	Not done