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. Author manuscript; available in PMC: 2017 Sep 9.
Published in final edited form as: Genes Immun. 2017 Mar 9;18(2):88–94. doi: 10.1038/gene.2017.3

Figure 1.

Figure 1

Summaries for PRS associations with sarcoidosis risk in the (A) European-Americans, (B) African-Americans samples, and (C) African-Americans accounting for the modifying effect of European ancestry. A variant including threshold of PT = 0.5 was used and the major histocompatibility complex was included where available. The Nagelkerke’s pseudo-R2 term and significance of model were calculated using PRSice21 for panels (A) and (B) and a likelihood ratio test for (C) (see Supplement) using nine inflammatory conditions as a prediction base: asthma (AS), Crohn’s disease (CD), celiac disease (CEL), multiple sclerosis (MS), primary biliary cirrhosis (PBC), rheumatoid arthritis (RA), systemic lupus erythematous (SLE), type 1 diabetes (T1D), and ulcerative colitis (UC).