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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Clin Cancer Res. 2016 Oct 27;23(11):2681–2690. doi: 10.1158/1078-0432.CCR-16-1467

Table 3.

Patient Demographics, Tumor Clinicopathologic Features and Genetic Characteristics of Patients with Circulating Tumor Cells based upon staining with cytokeratin and CD133.

Variable PanCK positive, CD133 positive, CD44 negative CTCs (n=40) Absence of PanCK positive, CD133 positive, CD44 negative CTCs (n=20) P-Value

Average Age (years) 65 (27–85) 64 (40–88) 0.76

Gender 0.26

 Male 27 (68%) 10 (50%)

 Female 13 (32%) 10 (50%)

Average CA19-9 483 (0.6–3758) 946 (1–9032) 0.55

CA 19-9 Level (n=46) 0.35

 High (> 36) 21 (66%) 7 (50%)

 Low (< 36) 11 (34%) 7 (50%)

Surgical Resection 0.64

 Whipple 29 (73%) 15 (75%)

 Distal pancreatectomy 9 (22%) 3 (15%)

 Total pancreatectomy 2 (5%) 2 (10%)

Average Tumor Size (cm) 3.2 (1.7) 3.3 (1.7) 0.81

Tumor Grade 0.90

 Well 2 (5%) 1 (5%)

 Moderate 21 (54%) 10 (50%)

 Poor 16 (41%) 9 (45%)

 Not specified

Positive lymph nodes 28 (70%) 14 (70%) >0.99

Positive margin 8 (20%) 4 (20%) >0.99

Stage 0.69

 Stage I 8 (20%) 4 (20%)

 Stage II 31 (78%) 15 (75%)

 Stage III 0 (0%) 1 (5%)

 Stage IV 1 (2%) 0 (0%)

Perineural invasion 31 (78%) 16 (80%) 0.99

Perivascular invasion 27 (68%) 13 (65%) 0.99

Neoadjuvant Chemotherapy 15 (38%) 9 (45%) 0.59

Adjuvant Chemotherapy 35 (88%) 17 (100%) 0.31