Table 1.
Characteristics of Study Population
| ln IL-61 (pg/mL/lymphocytes) n=509 |
Ln TNF-α1 (pg/mL/lymphocytes) n=509 |
||||
|---|---|---|---|---|---|
| N | Mean | (SD) | Mean | (SD) | |
| Age, years | |||||
| 39–50 | 31 | 8.854^ | (0.441) | 6.545^ | (0.604) |
| 51–60 | 104 | 8.981 | (0.716) | 6.788 | (0.764) |
| 61–70 | 238 | 9.152 | (0.647) | 7.058 | (0.740) |
| 71–80 | 136 | 9.244 | (0.593) | 7.122 | (0.855) |
| Sex | |||||
| Male | 496 | 9.132 | (0.647) | 6.994 | (0.788) |
| Female | 13 | 8.801 | (0.501) | 6.789 | (0.710) |
| BMI (kg/m2) | |||||
| <25 | 70 | 9.181 | (0.701) | 6.997 | (0.909) |
| 25–29.9 | 149 | 9.152 | (0.606) | 7.014 | (0.941) |
| ≥30 | 290 | 9.095 | (0.653) | 6.974 | (0.659) |
| Race2 | |||||
| White | 481 | 9.131 | (0.632) | 7.002 | (0.777) |
| Other | 22 | 8.973 | (0.901) | 6.721 | (0.924) |
| Education2 | |||||
| ≤ High School | 221 | 9.167 | (0.628) | 7.037 | (0.745) |
| > High School | 271 | 9.107 | (0.613) | 6.959 | (0.812) |
| Smoking Status2 | |||||
| Never | 108 | 8.898^ | (0.569) | 6.657^ | (0.750) |
| Former | 292 | 9.198 | (0.669) | 7.122 | (0.794) |
| Current | 104 | 9.159 | (0.589) | 6.972 | (0.677) |
| COPD2 | |||||
| No | 319 | 9.143 | (0.660) | 6.999 | (0.785) |
| Yes | 188 | 9.084 | (0.623) | 6.965 | (0.790) |
| Worked on a Farm, yrs2 | |||||
| <10 | 75 | 9.092 | (0.796) | 6.918 | (0.765) |
| 10–19.9 | 145 | 9.099 | (0.607) | 6.901 | (0.739) |
| 20+ | 281 | 9.153 | (0.608) | 7.057 | (0.812) |
Abbreviations and Definitions: BMI, body mass index; COPD, FEV1/FVC < 0.70.
1
Whole blood assay; organic dust- stimulated
2
Numbers don’t add up to 100% due to missing data
^
Significant difference between groups, overall test, p<0.05.