Table 3.

Paired tumor and adjacent liver analyses of choline and PtC metabolite levels in HCC (n = 31)

Metabolite	Mean value in tumors	Mean value in liver tissue	Wilcoxon p-value
Phosphocholine (pmol/mg tissue)	3538.04	1141.77	<0.0001
CDP-choline (ng/mg tissue)	72.61	46.31	0.0017
Total PtC (mcg/mg tissue)	16.7	18.3	0.1233
PtC species at:	(log area units/mg tissue)	log area units/mg tissue)
m/z 732.5537	7.51	7.11	<0.0001
m/z 734.5667	7.40	7.20	<0.0001
m/z 758.5677	8.08	8.30	<0.0001
m/z 760.5814	8.10	8.05	0.2151
m/z 780.5573	6.73	6.99	<0.0001
m/z 782.5692	7.66	7.84	0.0010
m/z 784.5815	7.65	7.66	0.9390
m/z 786.6014	7.88	7.95	0.1388
m/z 788.6106	7.33	7.17	0.0011
m/z 806.5683	7.14	7.52	<0.0001
m/z 808.5808	7.18	7.34	0.0004
m/z 810.5967	7.47	7.54	0.0414
m/z 812.6067	7.14	7.06	0.0355
m/z 832.5772	6.38	6.49	0.0204
m/z 834.5969	6.80	7.04	<0.0001
m/z 836.6099	6.47	6.61	0.0002

PtC, phosphatidylcholine; CDP-choline, citidine diphosphate choline; m/z, mass-to-charge ratio.