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. 2017 Apr 28;7:153. doi: 10.3389/fcimb.2017.00153

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Copyright © 2017 Huang and Hu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Forest plots of RCTs in patients with constipation comparing probiotics with placebo or other intervention. Random-effects models were used to analyze the MD and 95% CI. (A) Overall outcomes of the six studies. (B) Subgroup analysis by age. (C) Subgroup analysis by geographical area.