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. 2017 Apr 13;7(4):85. doi: 10.3390/nano7040085

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Doxorubicin (DOX) encapsulation with magnetic nanoparticle (MNP) through a linker of tripolyphosphate (TPP). (a) Synthesis of DOX-_TPP-MNP via complexation of the MNP with DOX and TPP. Morphology of (b) DOX-_TPP-MNP or (c) DOX-MNP using scanning electron microscopy (SEM) at 200× magnification, and energy-dispersive X-ray (EDAX) analysis of the energy profiles of DOX-_TPP-MNP or DOX-MNP. (d) Photograph of DOX-_TPP-MNP and DOX-MNP in a 1.5-mL microcentrifuge tube; a magnet was applied to the right side of microcentrifuge tube.