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. 2017 Apr 28;7:46675. doi: 10.1038/srep46675

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(A) Photograph of the WINCS Harmoni device; (B) Schematic diagram showing the functional components in WINCS Harmoni, including the neurochemical sensing and stimulation boards, charging components, Bluetooth transceiver, primary microcontroller, and control software in the base station; (C) Image and dimensions of the WINCS Harmoni delta sigma (ΔΣ) analog-to-digital converter (ADC) that enables four channels of simultaneous neurochemical recordings; (D) Typical calibration curves for each of the four neurochemical recording channels in WINCS Harmoni showing a linear relationship between dopamine oxidation current and dopamine concentration.