Table 1. A comparison of commonly available devices capable of FSCV.

	WINCS Harmoni (This Work)	WINCS42,71	UEI (Universal Electrochemical Instrument)72,73	P. Phillips’ FSCV System74,75	Pinnacle FSCV System (wireless system)76	WaveNeuro FSCV System77	Reference 600+78	EZstat-Pro79
Organization	Mayo Clinic	Mayo Clinic	University of North Carolina	University of Washington	Pinnacle	Pine Instruments	Gamry	NuVant Systems
Number of FSCV channels	4	1	4	4	1	1	1	1
Wireless capabilities	yes	yes	no	no	yes	no	no	no
Built in synchronized stimulator	yes	no	no	no	no	no	no	no
Voltage range	2 V – adjustable center	2.5 V – adjustable center	±10 V	±10 V	−0.6 V to + 1.5 V	± 3.3 V	± 12 V	± 10 V
Maximum linear scan rate	1200 V/s	1000 V/s	> 10,000 V/s	500 V/s	1000 V/s	5000 V/s	1500 V/s	500 V/s
Current range	± 1 μA, ± 2 μA, ± 3 μA, ± 4 μA, ± 5 μA, ± 6 μA, ± 7 μA, ± 8 μA	± 1.25 μA	2 μA default - defined by headstage	1.22 μA	5.6 μA, 50.6 μA	2 μA default - defined by headstage	11 ranges (60 pA–600 mA)	1 μA, 100 μA, 10 mA, 1 A
DAC resolution	16-bit	12-bit	16-bit	12-bit	18-bit	16-bit	16-bit	16-bit
DAC update rate	100 kS/s	100 kS/s	2 MS/s	1 MS/s	1000 S/voltammogram	2 MS/s	10 MS/s	250 kS/s aggregate (125 kS/s per channel)
Analysis software	WincsWare	WincsWare	HDCV	HDCV, TarHeel CV, Demon	Pinnacle FSCV software	HDCV	Framework	EZWare
Real-time pseudocolor plot display	yes	yes	yes	no	yes	yes	no	no
Real-time analysis and control	yes (via Application Program Interface)	no	no	no	no	no	no	no
Use in Clinical Studies	FDA physiologic device exception for OCD	Yes80,81,82	no	Yes83,84	no	no	no	no