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Pyrrolo[4,3,2-de]quinoline containing natural products screened against the PANC-1 cell line in this study consisting of: (i) makaluvamines A (1), C (2), H (4), D (7), G (8), J-L (9–11), P (12); (ii) damirones A (5), B (3), D (6); (iii) semisynthetic makaluvamine acetates 9-N-acetyl makaluvamine A (13), 9-N-acetyl makaluvamine B (14), 15-O-acetyl makaluvamine J (15), 8,15-O-diacetyl-8-hydroxy-5a,7,8a-trien-makaluvamine J (16); and (iv) ammosamide B (17).
