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Effect of TLR4 deficiency on protein degradation and inflammation after cast immobilization of mice. mRNA expression of Atrogin1(A), MuRF (B), TNF‐α (C), IL‐6 (D), F4/80 (E), and MCP‐1(F) were measured in wild‐type C3H/HeN and nonfunctional‐TLR4 C3H/HeJ mice after 14 days of cast immobilization (n = 5–6 each group). The results are expressed as mean ± standard error. **P < 0.01, *P < 0.05.
