Table 1. Enantioenrichment of Amino Acid Precursors Driven by d-Sugars (Scheme 3)a.
Reaction conditions: 0.25 M AM-I with 0.50 M sugar in H2O with 0.25 M NaOH at 22–24 °C; Ala-I (7 d), Phe-I (7 d), Trp-I (5 d). For reactions employing mixtures of sugars: 0.25 M in each sugar; Ala-I (8 d), Phe-I (7 d), Trp (7 d). Enantiomeric excess measured using chiral HPLC after derivatization of AM-II.