Table 4. Baseline z-scores by biomarker group.

	Two feature biomarker
	A-N- (N=93)	A+N- (N=49)	A+N+ (N=21)	A-N+ (N=27)	p value
Global z-score					0.00071
Mean (SD)	0.9 (0.8)	0.8 (0.6)	0.3 (0.8)	0.3 (0.9)
Median	0.9	0.8	0.5	0.2
Range	(-0.9-2.5)	(-0.6-2.1)	(-1.5-1.4)	(-1.2-2.6)
Memory z-score					0.00661
Mean (SD)	0.7 (0.9)	0.6 (0.8)	0.2 (0.9)	0.2 (0.8)
Median	0.8	0.6	0.2	0.2
Range	(-1.6-2.6)	(-1.0-2.0)	(-1.4-1.5)	(-0.9-2.3)
Language z-score					0.01061
Mean (SD)	0.7 (0.8)	0.5 (0.6)	0.2 (0.8)	0.3 (0.8)
Median	0.7	0.6	0.4	0.1
Range	(-1.5-2.5)	(-0.9-2.1)	(-1.2-1.7)	(-1.1-2.7)
Attention z-score					0.00421
Mean (SD)	0.8 (0.7)	0.8 (0.7)	0.3 (0.7)	0.2 (1.0)
Median	0.8	0.8	0.4	0.2
Range	(-1.1-2.4)	(-0.8-2.3)	(-1.2-1.3)	(-1.9-2.0)
Visual spatial z-score					0.06391
Mean (SD)	0.6 (1.0)	0.6 (0.8)	0.2 (1.0)	0.2 (1.1)
Median	0.7	0.4	0.4	0.0
Range	(-1.6-2.4)	(-1.0-2.5)	(-1.6-2.2)	(-2.3-2.3)

¹Kruskal Wallis

A-N- = amyloid negative/neurodegeneration negative; A+N- = amyloid positive/neurodegeneration negative; A-N+ = amyloid negative/neurodegeneration positive; A+N+ = amyloid positive/neurodegeneration positive; SD = standard deviation