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. 2017 Apr 28;18:18. doi: 10.1186/s40360-017-0128-7

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Cavities of Prostaglandin-endoperoxide synthase 2 (PDB 3NT1). a The two cavities 3NT1_2 (pale yellow) and 3NT1_3 (orange) define the two binding-sites of this protein in the Pisces dataset. The bound naproxen is also shown. b Cavity 3NT1_1, in red, covers the naproxen binding-site, but was excluded because of its size