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. 2017 Apr 27;14:94. doi: 10.1186/s12974-017-0866-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 10 — Activity of YY-1224 (YY) or Gb on PAF-AH level in the hippocampus of APP/PS1 Tg mice. a, b Effects of meloxicam on the pharmacological activity of YY or Gb in response to PAF-AH-immunoreactivity in the CA1 (a) and CA3 (b) regions of the hippocampus. c Effects of meloxicam on the pharmacological activity of YY or Gb in response to PAF-AH I α2 mRNA expression in the hippocampus. Veh vehicle for YY or Gb (10% tween-80 in sterile saline). Each value is the mean ± S.E.M of five animals. ^# P < 0.05, ^## P < 0.01 vs. vehicle + 0.5% Na-CMC; &P < 0.05 vs. Gb + 0.5% Na-CMC (two-way ANOVA was followed by Fisher’s LSD pairwise comparisons). Scale bar = 200 μm