Table 4. Independent associations between cardiometabolic risk markers, cortisol as well as cortisol:brain derived neurotrophic factor (BDNF) in an African male cohort.
| HbA1c | 24-h SBP | 24-h DBP | Silent ischaemia | |||||
| β (95% CI) | p-value | β (95% CI) | p-value | β (95% CI) | p-value | β (95% CI) | p-value | |
| Adjusted R2 | 0.16 | 0.29 | 0.21 | 0.12 | ||||
| Cortisol | 0.21 (0.0–0.4) | 0.04 | 0.23 (0.1–0.4) | 0.01 | 0.23 (0.1–0.4) | 0.01 | 0.01 0.18 (0.0–0.4) | 0.07 |
| GGT | - | 0.14 (0.0–0.3) | 0.10 | 0.22 (0.0–0.4) | 0.02 | - | ||
| Age | - | 0.30 (0.1–0.5) | < 0.01 | 0.20 (0.0–0.4) | 0.04 | 0.33 (0.1–0.5) | < 0.01 | |
| Log physical activity | – | 0.30 (0.1–0.5) | 0.02 | 0.28 (0.0–0.5) | 0.08 | – | ||
| Body surface area | - | 0.18 (–0.1–0.4) | 0.14 | 0.15 (–0.1–0.4) | 0.26 | – | ||
| Adjusted R2 | < 0.10 | 0.26 | 0.15 | 0.22 | ||||
| Cortisol:BDNF | 0.20 (0.0–0.4) | 0.03 | – | – | 0.40 (0.2–0.6) | < 0.01 | ||
| Log cGGT | – | – | – | – | ||||
| Age | 0.32 (0.1–0.5) | < 0.01 | – | – | 0.36 (0.2–0.5) | < 0.01 | ||
| Log physical activity | 0.29 (0.0–0.5) | 0.02 | – | – | 0.16 (0.0–0.4) | 0.09 | ||
| Body surface area | 0.21 (0.0–0.5) | 0.09 | – | – | – | |||
HbA1c, glycated haemoglobin; SBP, systolic blood pressure; DBP, diastolic blood pressure; log cGGT, log gamma-glutamyl transferase.