TABLE 5.

BODIPY-lipids with similar FA chain lengths are metabolized differently depending on the BODIPY variant, BODIPY-lipid class, and cholesterol content of the diet

	Products of BODIPY-Lipid Fed in LF/LC Diet				Products of BODIPY-Lipid Fed in LF/HC Diet
BODIPY-Lipid	FA	PL	TG	CE	FA	PL	TG	CE
BODIPY FL-C12	No signal	40.1 ± 5.2a	16.9 ± 1.7	42.9 ± 3.6a	No signal	29.3 ± 0.2a	19.5 ± 2.2	51.2 ± 2.0a
BODIPY(558/568)-C12	15.8 ± 3.0	No signal	52.5 ± 1.2	31.7 ± 3.0	45.9 ± 17.2	No signal	34.1 ± 11.8	20.0 ± 8.9
Cholesterol BODIPY FL-C12	No signalb	27.2 ± 0.6b	16.8 ± 9.9b	56.0 ± 10.5b	No signal	30.0 ± 7.7	26.2 ± 7.3	43.7 ± 7.6
Cholesterol BODIPY(576/589)-C11	No signalb	No signalb	No signalb	No signalb	No signal	No signal	58.9 ± 3.8	41.1 ± 3.8

Fluorescent products of BODIPY-lipids fed to larval zebrafish in a HF/HC meal are quantitated by class as percentage of total fluorescence ± standard deviation.

^aP < 0.05 when LF/LC and LF/HC groups are compared by Student’s t-test.

^bn = 2. For all other groups, n = 3.