TABLE 1.

ApoC-III variants and their hydrophobic moment

ApoC-III Variant	<μH> (kcal/mol residue)
WT	0.74
F47A/L50A	0.70
W42A/F47A	0.68
W42A/F47A/L50A	0.64
W42A/F47A/F64A/W65A	0.61
W54A/F61A/F64A/W65A	0.63

Mean hydrophobic moment (<μ_H>) of apoC-III variants. Hydro­phobic moments (μ_H) were calculated for the three predicted α-helices within each peptide as previously described (57) by using the Goldman, Engelman, and Stetiz (GES) hydrophobicity scale (58). The GES scale calculates the average free energy change of each amino acid on transition from water to oil. The μ_H of all three helices were averaged and represent the mean hydrophobic moment (<μ_H>) for each peptide.