TABLE 1.

Enteroids express key apolipoproteins and enzyme machinery for lipid absorption, synthesis, and secretion

Gene	Basal Enteroid mRNA Expression (% Whole Tissue)	Differentiated Enteroid mRNA Expression (% Whole Tissue)	P
apoA-l	3.72 ± 2.19	20.01 ± 11.77	NS
apoC-lll	2.34 ± 0.79	19.23 ± 12.63	NS
apoA-IV	2.34 ± 0.83	13.10 ± 4.60	<0.05a
apoB-48	5.75 ± 3.26	5.12 ± 2.65	NS
CD36	7.68 ± 6.26	11.08 ± 6.03	NS
ACSL5	3.35 ± 1.97	3.30 ± 1.98	NS
FABP2	5.46 ± 2.72	16.98 ± 8.00	NS
ACAT2	5.07 ± 2.40	14.84 ± 6.17	NS
NPC1L1	114.15 ± 65.14	161.05 ± 111.97	NS
MTTP	16.39 ± 10.06	36.39 ± 19.47	NS
MGAT2	12.89 ± 4.13	21.30 ± 4.32	NS
DGAT1	13.55 ± 7.44	34.62 ± 14.85	NS
DGAT2	22.39 ± 14.43	48.83 ± 28.63	NS

mRNA expression is expressed as a percent of mRNA expression in whole duodenum. Results are mean ± SEM; n = 3–6 unique enteroid lines (all C57Bl/6J WT). FABP2, fatty-acid binding protein 2; ACSL5, acyl-CoA synthetase;

^aP < 0.05 comparing basal enteroid expression to differentiated expression.