TABLE 1.

Altered lipid content of the lungs of bone-marrow transplanted mice

	Wild-type Recipient		Abcg1−/−−/− Recipient
	Wild-type Donor	Abcg1−/−−/− Donor	Wild-type Donor	Abcg1–/– Donor
Lung weight (mg)	41.2 ± 1.2	48.4 ± 1.4a	50.7 ± 2.0b	75.7 ± 2.4a,b
Lung lipids (μg/mg)
Total cholesterol	0.66 ± 0.1	2.56 ± 0.2a	3.32 ± 0.6b	8.34 ± 1.3a,b
Unesterified cholesterol	0.46 ± 0.1	1.04 ± 0.1a	2.84 ± 0.4b	3.42 ± 0.4b
Esterified cholesterol	0.20 ± 0.1	1.52 ± 0.2a	0.48 ± 0.2	4.92 ± 1.4a,b
Phospholipids	1.86 ± 0.3	4.34 ± 0.4a	6.50 ± 1.1b	11.09 ± 2.7a,b

Tissue lipid levels were determined as described in the Materials and Methods. Data are expressed as mean ± SEM (n = 4–6 mice/group). Significance was determined by two-way ANOVA followed by Bonferroni correction.

^aP < 0.01 wild-type versus Abcg1^−/− donor.

^bP < 0.01 wild-type versus Abcg1^−/− recipient.