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Inhibition of VCAM-1 expression by HDL. HDLs from carriers of LCAT deficiency and controls were tested for their ability to reduce VCAM-1 expression induced by TNFα stimulation in endothelial cells. Data are expressed as percentage of VCAM-1 concentration in the conditioned media of TNFα-stimulated cells; n = 6 for homozygotes (pooled in two preparations), n = 10 for heterozygotes and controls. PTrend is reported.
