TABLE 2.
Carriersa | Controls | P | |
n | 15 | 35 | |
Age (years) | 43.9 ± 3.0 | 44.1 ± 1.9 | 0.97 |
Gender (male/female) | 8/7 | 19/16 | 0.95 |
BMI (kg/m2) | 23.4 ± 0.8 | 23.7 ± 0.5 | 0.75 |
Total cholesterol (mg/dl) | 160.8 ± 12.0 | 199.1 ± 6.8 | 0.005 |
LDL-C (mg/dl) | 105.2 ± 9.8 | 124.0 ± 5.3 | 0.07 |
HDL-C (mg/dl) | 32.9 ± 5.4 | 56.1 ± 2.2 | <0.0001 |
Triglycerides (mg/dl) | 113.1 ± 12.4 | 95.1 ± 9.2 | 0.27 |
FMD | 0.237 ± 0.025 | 0.304 ± 0.030 | 0.18b |
Data are expressed as mean ± SEM.
Comprising 5 homozygotes and 10 heterozygotes, pooled for statistical analysis.
P adjusted for HDL-C = 0.22.