Table 1.
A comparison of OSTI and [Phe9]-OSTI against trypsin, chymotrypsin and tryptase
Peptide name | Sequence | Net charge | Trypsin inhibition Ki | Chymotrypsin inhibition Ki | Tryptase inhibition Ki |
---|---|---|---|---|---|
OSTI | AALKGCWTKSIPPKPCF-amide | 3.9 | 0.3 ± 0.04 nM | N/A | 2.5 ± 0.6 μM |
[Phe9]-OSTI | AALKGCWTFSIPPKPCF-amide | 2.9 | N/A | 1.0 ± 0.1 μM | N/A |