Table 1.

Divergent amino acid (aa) positions between genotype B and genotype C isolates in the preS1, preS2, and S domains.

preS1 aa Position

10

35

39

45

48

51

54

57

60

84

108

115

Genotype B (2246 isolates)

K

K

E

L

H

N

D

K

V

L

L

T

Genotype C (2227 isolates)

Q

G

N

F

N

H

E

Q

A

I

I

S

preS2 aa Position

130

132

138

152

154

155

156

158

160

165

167

172

Genotype B (2419 isolates)

T

Q

A

S

A

Q

N

V

A

L

K

V

Genotype C (2377 isolates)

A

L

G

N

V

P

T

A

P

F

R

A

S aa Position

4

5

8

24

45

47

49

56

57

59

Genotype B (4224 isolates)

I

A

L

K

T

V

L

Q

I

S

Genotype C (7183 isolates)

T

T

F

R

A

T

P

P

T

N

64

85

110

113

126

143

160

161

200

213

Genotype B (4224 isolates)

C

C

I

S

T

T

K

Y

F

M

Genotype C (7183 isolates)

S

F

L

T

I

S

R

F

Y

L