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. 2017 Apr 7;9(4):72. doi: 10.3390/v9040072

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Distance-based species tree containing 86 representative members from 10 families of order Megavirales included in our study. Species tree is prepared by using SDM approach implemented on the orthoMCL output (output 1). The tree depicts two major clades: one clade with Poxviridae (blue), Iridoviridae (red) and Ascoviridae (aqua) and the other clade including Phycodnaviridae (green), marseillevirus (yellow), pithovirus (bluish green), Mimiviridae (Voilet), pandoravirus (pink) Asfarviridae (olive green) and faustovirus (black). Megavirale family tree inferred from this species tree is further used as guide tree for tagging evolutionary scenarios of OGs predicted by our workflow.