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. 2017 Apr 1;13(4):925. doi: 10.15252/msb.20167347

Figure 6. Function‐switching mechanism and decomposability of hybrid circuits.

Figure 6

  1. How is hybrid C capable of performing both functions upon a change in the context signal? We use the simplified 2‐cell model of Box 2 with parameters (w A = 0.41, w B = 5.49, w C = −0.30, α A = 6.93, α D = 12.79). The context signal changes the position and number of steady states through a pitchfork bifurcation (Strogatz, 2014) (Bifurcation 2). This bifurcation drives the trajectory to access different attractors found in regions of the phase portrait corresponding to induction (θ 2) and inhibition (θ 4) patterns, respectively.
  2. Phase portraits of the mono‐functional modules (induction and inhibition) that build hybrid C.
  3. The nullclines of hybrid C can be decomposed into sub‐parts which correspond to the induction and inhibition modules.