Fig. 1.

dAPE representation of the evolution of two different homorepeats. Gaps are represented by dashes, and aligned regions in grey. Only fragments of the full alignments are shown, for simplicity. Abbreviations of the organisms' names can be found in Supplementary Table S1. (a) Evolution of a polyQ region (in blue, human coordinates: 197-225), using default parameters and ′ENSP00000244769′ (human Ataxin-1) as query. The polyQ run of Ataxin-1 appeared in primates and seems to have grown in length during its evolution. (b) Evolution of a polyP region (in red, human coordinates: 185-202), using default parameters and ′ENSP00000262293′ (human PRR11) as query. The polyP run of PRR11 seems to have appeared before the emergence of tunicates, and displays great length variability