Table 1.
Baseline characteristics of cardiometabolic risk factors and follow-up status by latent class
| N | Overall 3666 |
Class 1 1437 (39%) |
Class 2 1068 (29%) |
Class 3 801 (22%) |
Class 4 360 (10%) |
|---|---|---|---|---|---|
| Age (year) | 37 (30–45) | 35 (28–42) | 39 (31–47) | 37 (30–45) | 44 (37–52) |
| Sex (male %) | 41.8 | 36.3 | 41.8 | 49.3 | 47.5 |
| BMI (kg/m2) | 25.2 (22.1–28.4) | 23.8 (20.8–27.0) | 26.1 (23.1–29.0) | 25.8 (22.8–28.5) | 27.1 (24.2–30.4) |
| Height (cm) | 156 (150–163) | 155 (150–162) | 156 (150–163) | 157 (151–165) | 157 (150–163) |
| Waist circumference (cm) | 83 (75–91) | 79 (71–87) | 85 (78–93) | 85 (78–92) | 89 (82–96) |
| TC (mmol/L) | 4.6 (4.0–5.3) | 4.4 (3.9–5.1) | 4.7 (4.2–5.3) | 4.7 (4.1–5.4) | 4.9 (4.4–5.5) |
| LDL (mmol/L) | 2.9 (2.4–3.4) | 2.7 (2.3–3.3) | 3.0 (2.5–3.5) | 3.0 (2.5–3.5) | 3.1 (2.6–3.5) |
| HDL (mmol/L) | 1.1 (0.9–1.2) | 1.1 (0.9–1.2) | 1.0 (0.9–1.2) | 1.0 (0.9–1.2) | 1.0 (0.9–1.2) |
| Triglycerides (mmol/L) | 1.3 (0.9–1.8) | 1.1 (0.8–1.5) | 1.3 (1.0–1.8) | 1.4 (1.0–1.9) | 1.6 (1.2–2.2) |
| Smoking (%) | 17.6 | 16.6 | 16.4 | 19.1 | 21.4 |
| Glucose0 (mmol/L) | 5.1 (4.8–5.5) | 4.9 (4.6–5.2) | 5.2 (4.9–5.5) | 5.3 (5.0–5.7) | 5.7 (5.4–6.2) |
| Glucose30 (mmol/L) | 8.2 (6.9–9.5) | 6.6 (5.8–7.2) | 8.5 (8.0–9.0) | 9.7 (9.1–10.4) | 10.9 (10.3–11.8) |
| Glucose120 (mmol/L) | 5.5 (4.7–6.4) | 4.8 (4.2–5.4) | 6.4 (5.8–7.0) | 4.9 (4.3–5.6) | 8.5 (7.7–9.6) |
| Insulin0 (pmol/L) | 47 (32–68) | 40 (29–59) | 51 (36–71) | 47 (32–69) | 60 (47–83) |
| Insulin30 (pmol/L) | 325 (224–506) | 298 (204–455) | 345 (240–549) | 340 (235–542) | 358 (235–523) |
| Insulin120 (pmol/L) | 240 (164–398) | 191 (147–292) | 291 (183–479) | 233 (167–373) | 435 (293–675) |
| BIGTT-SI0-30-120 | 8.1 (5.0-11.0) | 10.4 (7.8-12.9) | 6.8 (4.4-9.4) | 7.7 (5.0-10.1) | 4.2 (2.5-5.8) |
| BIGTT-AIR0-30-120 | 1974 (1489–2695) | 2156 (1712–2863) | 2081 (1594–2860) | 1556 (1207–2218) | 1573 (1197–2211) |
| Glucose tolerance status (%) | |||||
| NGT | 86.7 | 98.8 | 88.1 | 92.5 | 21.4 |
| iIFG | 4.1 | 1.0 | 4.2 | 7.5 | 8.1 |
| iIGT | 6.6 | 0.1 | 7.1 | 0.0 | 45.8 |
| IFG + IGT | 2.6 | 0.0 | 0.6 | 0.0 | 24.7 |
| Follow-up time (y) | 1.9 (1.3–2.2) | 1.9 (1.4–2.2) | 1.8 (1.3–2.2) | 1.9 (1.3–2.2) | 1.8 (1.3–2.3) |
| Missing follow-up (%) | 29.9 | 30.5 | 32.1 | 28.5 | 23.9 |
| DM at follow-up (%)* | 5.3 | 0.6 | 4.0 | 6.6 | 23.4 |
*
Among those who participated at follow-up