Fig. 1.

The distribution of scores for RNA–RNA interaction prediction algorithms. (A) RNAduplex gave the highest median TPR (sensitivity) followed by IntaRNA. (B) RNAup was the most precise algorithm based on PPV score followed by the other accessibility based methods IntaRNA and RNAplex. (C) RNAup was the best prediction algorithm based on median MCC score, with IntaRNA and RNAplex giving similar scores. RactIP produced the worst overall MCC (Color version of this figure is available at Bioinformatics online.)