Table 1.
Sequences (5′ → 3′) | |
---|---|
Pri-miRNA | A: GAU ACU AUA CUG AGA GCA UUC CGU UAU GUA GCA UUU CUU GGU UGU GAG GGG UUG UGC |
Drosha-DGCR8 (Section 3.1) | B: AAG AAG AAU CUC ACG AUC AAG GAA UGC UAC AU |
Strand C was Cy5-labeled | C: AAC GGA GuG UUU GAG CAG ACC CGC GAC U |
dsRNA | D: AAG AAG AAU CUC ACG AUC AAG GAA UGC uAC AUA A |
Drosophila Dicer-2 (Section 3.2.1) | E: pCGG AGU GUU UGA GCA GAC CCG CGA UCU UUC AUU GCC |
Strand D was Cy3-labeled | F: CTC AAA CAC TCC GTT ATG TAG CAT TC |
G: pGGC AAU GAA AGA UCG CGG GUC UGC UCA AAC ACU CCG UUA UGU AGC | |
H: pAUU CCU UGA UCG UGA GAU UCU UCU U | |
I: ACG ATC AAG GAA TGC TAC ATA ACG GA | |
pre-let-7a-1 | J: UGA GGU AGU AGG UUG UAU AGU UUU AGG GUC ACA CC |
Human Dicer (Section 3.2.2) | K: pCAC CAC UGG GAG AUA ACU AUA CAA UCU ACU GUC uUU CU |
Strand K was Cy5-labeled | |
Cy3-dA15 (section: 3.3) | X: Cy3-AAA AAA AAA AAA AAA |
p indicates phosphate; u represents dye-labeled nucleotide