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Impact of experimental factors on the efficacy of (A) RIPreC and (B) RIPerC/RIPostC. WMD and the corresponding 95% CI for each variable were obtained by subgroup stratification. However, the reported P-value was obtained by meta-regression to reduce false-positive findings. Studies that used either mice or rats were grouped as ‘small animals’, and those using rabbits or pigs were grouped as ‘large animals’. A P-value of < 0.01 was considered significant.
