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. 2016 Oct 8;20(3):228–236. doi: 10.1093/ijnp/pyw089

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© The Author 2016. Published by Oxford University Press on behalf of CINP.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Effects of MGS0039 and ketamine on the brain-derived neurotrophic factor (BDNF) and TrkB phosphorylation in the brain regions. (a) Expression of BDNF in the brain regions. (b) Ratio of phosphorylated TrkB (p-TrkB) to total TrkB in the brain regions. (c) Expression of GluA1 in the brain regions. (d) Expression of postsynaptic density protein 95 (PSD95) in the brain regions. The value was expressed as a percentage of that of control mice. The values represent the mean ± SEM (n = 5 or 6). *P < .05, **P < .01, ***P < .001 compared with the vehicle + stress group. Ket, ketamine; MGS, MGS0039; Veh, vehicle.