Table 1. Results and suggested interpretations of skin swab samples from patients with AD and healthy controls using the BD Max StaphSR assay.
Results displayed | Targets* | AD | Control | ||||
---|---|---|---|---|---|---|---|
SA | MRSA | MREJ | nuc | mecA/mecC | (N = 213) | (N = 31) | |
Pos | Pos | D | D or ND | D | MRSA | 6 | - |
Pos | Neg | ND | D | ND | MSSA | 27 | 1 |
Pos | Neg | ND | D | D | Mixed MSSA & MRnonSA | 33 | - |
Pos | Neg | D | D or ND | ND | SA empty-cassette variant | 3 | - |
Neg | Neg | ND | ND | D | MRnonSA | 43 | 7 |
Neg | Neg | ND | ND | ND | nonSA & nonMRSA | 101 | 23 |
*The positive Ct value ranges for MREJ, nuc, and mecA/mecC were 25.8–38.6, 23.5–38.6, and 24.5–39.4, respectively. The detection rate of SA was significantly higher in patients with AD than that in controls (P=0.0008).
Abbreviations: AD, atopic dermatitis; D, detected; MRnonSA, methicillin-resistant non–Staphylococcus aureus; MRSA, methicillin-resistant Staphylococcus aureus; MSSA, methicillin-susceptible Staphylococcus aureus; ND, not detected; Neg, negative; nonMRSA, non-methicillin-resistant Staphylococcus aureus; nonMSSA, non-methicillin-susceptible Staphylococcus aureus; Pos, positive; SA, Staphylococcus aureus; SA empty-cassette variant, Staphylococcus aureus carrying a genetic element lacking mecA.