Figure 1.

Mean (SD) aripiprazole concentration-time profiles after deltoid or gluteal injection of aripiprazole once-monthly 400 as single- or multiple-dose administrations. Because data are from multiple trials, only time points that were common in all trials are displayed. In multiple-dose studies (injections given every 28 d), samples at days 28, 56, 84, and 112 are predosing concentrations (trough levels), and more frequent sampling was done at steady state from days 112 to 140. Historical gluteal multiple-dose data are from an open-label, parallel-arm, multiple-dose, 24-week study (Mallikaarjun et al., 2013).