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. 2017 Apr 28;12(4):e0176725. doi: 10.1371/journal.pone.0176725

Fig 2. Quality assessment of the social defeat model.

Fig 2

(A) Significant decreases in body weight were found inthe socially defeated group (n = 9) compared with the control group (n = 8). In the FST, the socially defeated group showed a significant decrease in sucrose preference (B) and sucrose consumption (C) compared with the control group. In the OFT, socially defeated rats did not significantly differ from control rats in total distance (D), time spent in center (E) and number of rearing behaviors (F). In the EPM, there were no significant differences between two experimental groups, including frequency (G) and time (H) spent in open arms, as well as in closed arms (I, J). In the FST, longer immobility time was found in socially defeated rats (K). *P< 0.05.