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. 2017 Apr 28;12(4):e0176725. doi: 10.1371/journal.pone.0176725

Fig 5. Ingenuity pathways analysis of differential metabolites.

Fig 5

The network “Hereditary Disorder, Neurological Disease, Lipid Metabolism” was the most significantly altered network between socially defeated group (n = 9) and control group (n = 8), with a score of 26. The network includes 10 out of the 25 metabolites uploaded on the Ingenuity Pathway Analysis reference database. These metabolites are functionally related and have a role in the same network centred on NF-κB, MAPK and AKT signaling cascade. Red indicates metabolites that were upregulated, while green indicates metabolites that were downregulated, in the social defeat group compared with the control group.