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. 2017 Jan 13;26(5):989–1002. doi: 10.1093/hmg/ddx015

Figure 4.

Figure 4

The BP risk (minor) allele at the SLC4A7 locus is associated with increased NBCn1 availability at the plasma membrane in VECs. (A) shows the protein immunoblots for NBCn1 with VEC samples stratified by genotype at rs13082711, and quantified in (B) P > 0.05 by Mann-Whitney U-test. (C) Subcellular fractionation samples from VECs, showing that the BP risk (minor) allele at the SLC4A7 locus is associated with increased NBCn1 signal in the membrane fraction. 2 μg protein of each cellular fraction was loaded in each lane. n=8 each group. *P<0.05 by Mann-Whitney U-test.