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Mitochondrial DNA (mtDNA), mitochondrial transcription factor A (Tfam), peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), and cytochrome c oxidase subunit 4 isoform 1 (COX4-i1), nuclear respiratory factor 1 (Nrf1) mRNA expressions were measured by real-time PCR as described in methods. Data are shown as mean±SE of 6 mice per group. *p<0.05 vs. WT.
