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. 2017 Apr 28;12(4):e0176763. doi: 10.1371/journal.pone.0176763

Fig 1. NQO1 expression correlates with 17-AAG effectiveness in multiple cancer types.

Fig 1

Green color represents negative Spearman’s rank correlation coefficients between NQO1expression and 17-AAG EC50 in the CCLE (A) and IC50 (EC50 was not available) in GDSC (B). These results indicate that 17-AAG works better when NQO1 expression is higher. Only p < 0.05 correlations are shown.